Sar-[D-Phe8]-des-Arg9-Bradykinin acetate | TP1917L1

Sar-[D-Phe8]-des-Arg9-Bradykinin acetate | TP1917L1 | TargetMol Chemicals

CAS: TP1917L1

Smiles: CNCC(=O)N[C@@H](CCCN=C(N)N)C(=O)N1CCC[C@H]1C(=O)N2CCC[C@H]2C(=O)NCC(=O)N[C@@H](CC3=CC=CC=C3)C(=O)N[C@@H](CO)C(=O)N4CCC[C@H]4C(=O)N[C@H](CC5=CC=CC=C5)C(=O)O.CC(O)=O

Formula: C49H70N12O13

Pathway: GPCR/G Protein

Target: Bradykinin Receptor

Receptor: N/A

Bioactivity: Sar-[D-Phe8]-des-Arg9-Bradykinin acetate is a potent and selective bradykinin B1 receptor agonist (EC50 = 9.02 nM in rabbit aorta) that is resistant to aminopeptidase, kininase I and II (ACE) and neutral endopeptidase cleavage. Exhibits hypotensive and angiogenic activity in vivo.

Molecular Weight: 1035, 15