SB 224289 | T19690

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€364.00 - €1,701.00
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TMC-T19690
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Product Overview

SB 224289 | T19690 | TargetMol Chemicals

CAS: 180083-23-2

Smiles: CN1CCC2(COc3cc4CCN(C(=O)c5ccc(cc5)-c5ccc(cc5C)-c5noc(C)n5)c4cc23)CC1

Formula: C32H32N4O3

Pathway: N/A

Target: N/A

Receptor: N/A

Bioactivity: SB 224289 is a selective antagonist of 5-HT1B receptor with pKi of 8.2. It is a centrally active following oral administration in vivo. SB 224289 displays 60-fold selectivity over 5-HT1D, 5-HT1A, 5-HT1E, 5-HT1F, 5-HT2A and 5-HT2C receptors in radioligand binding and functional assays.

Molecular Weight: 520, 633

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