Product Overview
SB-265610 | T16850 | TargetMol Chemicals
CAS: 211096-49-0
Smiles: Brc1ccccc1NC(=O)Nc1ccc(C#N)c2nn[nH]c12
Formula: C14H9BrN6O
Pathway: Autophagy|||GPCR/G Protein|||Immunology/Inflammation
Target: CXCR
Receptor: N/A
Bioactivity: SB-265610 is a nonpeptide and allosteric CXCR2 antagonist. SB-265610 blocks rat cytokine-induced neutrophil chemoattractant-1 (CINC-1)-induced calcium mobilization and neutrophil chemotaxis (IC50s: 3.7 nM and 70 nM, respectively).
Molecular Weight: 357, 171
