Product Overview
SB-431542 | T1726 | TargetMol Chemicals
CAS: 301836-41-9
Smiles: NC(=O)c1ccc(cc1)-c1nc(c([nH]1)-c1ccccn1)-c1ccc2OCOc2c1
Formula: C22H16N4O3
Pathway: Angiogenesis|||Stem Cells|||Tyrosine Kinase/Adaptors
Target: ALK|||TGF-beta/Smad
Receptor: N/A
Bioactivity: SB-431542 is a potent and selective inhibitor of ALK5 (IC50: 94 nM) and is also an inhibitor of ALK4 (IC50: 140 nM) and ALK7.
Molecular Weight: 384, 395
