Product Overview
SC-43 | T8478 | TargetMol Chemicals
CAS: 1400989-25-4
Smiles: FC(F)(F)c1cc(NC(=O)Nc2cccc(Oc3ccc(cc3)C#N)c2)ccc1Cl
Formula: C21H13ClF3N3O2
Pathway: Apoptosis|||JAK/STAT signaling|||Metabolism|||Stem Cells
Target: Apoptosis|||Phosphatase|||STAT
Receptor: N/A
Bioactivity: SC-43 is a potent and orally active agonist of SHP-1 (PTPN6). SC-43 inhibits the phosphorylation of STAT3 and induces cell apoptosis, and with anti-fibrotic and anticancer effects.
Molecular Weight: 431, 8
