Product Overview
SCH-37370 | T19686 | TargetMol Chemicals
CAS: 117796-52-8
Smiles: CC(=O)N1CCC(CC1)=C1c2ccc(Cl)cc2CCc2cccnc12
Formula: C21H21ClN2O
Pathway: Others
Target: Platelet aggregation
Receptor: N/A
Bioactivity: SCH-37370 is an effective and orally active dual antagonist of platelet-activating factor and histamine. Sch 37370 blocks the binding of [3H]pyrilamine to histamine-H1 receptors in rat brain membranes. Sch 37370 selectively inhibits PAF-induced aggregation of human platelets (IC50 : 0.6 mM) and also competes with PAF binding to specific sites in membrane preparations from human lungs (IC50 : 1.2 mM).
Molecular Weight: 352, 86
