Product Overview
SCH772984 HCl | T23337 | TargetMol Chemicals
CAS: T23337
Smiles: O=C(N1CCN(C2=CC=C(C3=NC=CC=N3)C=C2)CC1)CN4CC[C@@](/C(O)=N/C5=CC(C(C6=CC=NC=C6)=NN7)=C7C=C5)([H])C4.Cl
Formula: C33H34ClN9O2
Pathway: MAPK|||Others
Target: ERK|||Others
Receptor: N/A
Bioactivity: SCH772984 HCl is a selective inhibitor of ERK1/2 that displays behaviors of both type I and type II kinase inhibitors, with IC50s of 4 and 1 nM, respectively. SCH772984 HCl has nanomolar cellular potency in tumor cells with mutations in BRAF, NRAS, or KRA
Molecular Weight: 624, 17
