Product Overview
SCH900776 (S-isomer) | T3700 | TargetMol Chemicals
CAS: 891494-64-7
Smiles: Cn1cc(cn1)-c1cnn2c(N)c(Br)c(nc12)[C@H]1CCCNC1
Formula: C15H18BrN7
Pathway: Cell Cycle/Checkpoint
Target: Chk|||CDK
Receptor: N/A
Bioactivity: SCH900776 (S-isomer) is an effective, specific and orally bioavailable inhibitor of checkpoint kinase Chk1 (IC50: 3 nM). It also inhibitors Chk2 (IC50: 1500 nM) and cyclin-dependent kinase CDK2 (IC50: 160 nM).
Molecular Weight: 376, 262
