Product Overview
Selamectin | T4059 | TargetMol Chemicals
CAS: 220119-17-5
Smiles: CO[C@H]1C[C@H](O[C@H]2[C@@H](C)\C=C\C=C3/CO[C@@H]4\C(=N\O)C(C)=C[C@@H](C(=O)O[C@H]5C[C@@H](C\C=C2/C)O[C@@]2(CC[C@H](C)[C@H](O2)C2CCCCC2)C5)[C@]34O)O[C@@H](C)[C@@H]1O
Formula: C43H63NO11
Pathway: Membrane transporter/Ion channel|||Microbiology/Virology|||Neuroscience
Target: Chloride channel|||P-gp|||Parasite
Receptor: N/A
Bioactivity: Selamectin is a macrocyclic lactone derivative of ivermectin, an anthelmintic that potentiates glutamate- and GABA-gated chloride channel opening in nematodes. In an H. contortus larval development assay, selamectin (0.1 μg/ml) shows the effect of growth inhibition.
Molecular Weight: 769, 973