Product Overview
Selumetinib | T6218 | TargetMol Chemicals
CAS: 606143-52-6
Smiles: Cn1cnc2c(F)c(Nc3ccc(Br)cc3Cl)c(cc12)C(=O)NOCCO
Formula: C17H15BrClFN4O3
Pathway: Apoptosis|||MAPK
Target: Apoptosis|||ERK|||MEK
Receptor: N/A
Bioactivity: Selumetinib (AZD6244) is an effective, specific inhibitor of MEK1 and ERK1/2 phosphorylation (IC50: 14/10 nM).
Molecular Weight: 457, 68
