Product Overview
Semialactone | TN4987 | TargetMol Chemicals
CAS: 366450-46-6
Smiles: C\C1=C\C[C@H](O)C(=C)[C@H]2CC[C@]3(COC1=O)[C@@H]2CC[C@H]1[C@@]3(C)CCC2C(C)(C)[C@@]3(O)CC[C@]12CO3
Formula: C30H44O4
Pathway: Others
Target: Others
Receptor: N/A
Bioactivity: Semialactone shows inhibitory activities on human acyl-CoA:cholesterol acyltransferase(hACAT)1 with IC50 values of 79.1 uM and on human hACAT2 with IC50 values of 76.9 uM, it may be effective in the prevention and treatment of hypercholesterolemia or atherosclerosis via inhibitory effect on hACAT.
Molecular Weight: 468, 7