Product Overview
Seneciphylline | TN1078 | TargetMol Chemicals
CAS: 480-81-9
Smiles: [H][C@]12CCN3CC=C(COC(=O)[C@](C)(O)C(=C)C\C(=C\C)C(=O)O1)[C@]23[H]
Formula: C18H23NO5
Pathway: Metabolism|||oxidation-reduction
Target: P450|||GST
Receptor: N/A
Bioactivity: Seneciphylline, one of the hepatotoxic pyrolizidine alkaloids, has mutagenic activity in Drosophila and their transfer into rat milk.Seneciphylline can significantly increased the activities of epoxide hydrase and glutathione-S-transferase but cause reduction of cytochrome P-450 and related monooxygenase activities.
Molecular Weight: 333, 384
