Product Overview
Serratenediol | TN4999 | TargetMol Chemicals
CAS: 2239-24-9
Smiles: CC1(C)[C@@H](O)CC[C@@]2(C)[C@H]1CC[C@@]1(C)CC3=CC[C@H]4C(C)(C)[C@@H](O)CC[C@]4(C)[C@H]3CC[C@H]21
Formula: C30H50O2
Pathway: Apoptosis|||Chromatin/Epigenetic|||DNA Damage/DNA Repair|||Proteases/Proteasome
Target: BCL|||PARP|||Caspase
Receptor: N/A
Bioactivity: Serratenediol demonstrates strong inhibitory effects on the Epstein-Barr virus early antigen (EBV-EA) activation without showing any cytotoxicity, its effects being stronger than that of a representative control, oleanolic acid. Serratenediol can promote the proliferation rate, alkaline phosphate(ALP) activity and some osteogenic gene expression of osteoblasts. Serratenediol also has significant and dose-dependent growth inhibitory effects on HL-60 cells via regulating the ratio of Bax/Bcl-xL.
Molecular Weight: 442, 7