Product Overview
Sesamol | T3676 | TargetMol Chemicals
CAS: 533-31-3
Smiles: Oc1ccc2OCOc2c1
Formula: C7H6O3
Pathway: Apoptosis|||PI3K/Akt/mTOR signaling
Target: Apoptosis|||AMPK
Receptor: N/A
Bioactivity: Sesamol could decrease lung inflammation and lipopolysaccharide (LPS)-induced lung injury in rats. Sesamol ameliorates inflammatory and oxidative damage by upregulating AMPK activation and Nrf2 signaling and blocking the NF-κB and MAPK signaling pathways and inhibits melanin biosynthesis by down-regulating tyrosinase activity and melanin production via regulation of gene expression of melanogenesis-related proteins through modulation of MITF activity, which promotes phosphorylation of p38 and JNK in melan-a cells.
Molecular Weight: 138, 122
