Product Overview
SGC0946 | T3082 | TargetMol Chemicals
CAS: 1561178-17-3
Smiles: CC(C)N(CCCNC(=O)Nc1ccc(cc1)C(C)(C)C)C[C@H]1O[C@H]([C@H](O)[C@@H]1O)n1cc(Br)c2c(N)ncnc12
Formula: C28H40BrN7O4
Pathway: Chromatin/Epigenetic
Target: Histone Methyltransferase
Receptor: N/A
Bioactivity: SGC0946 is a highly effective and specific DOT1L methyltransferase inhibitor (IC50: 0.3 nM); selectively kill mixed lineage leukemia cells.
Molecular Weight: 618, 577