Product Overview
SGE-516 | T28766 | TargetMol Chemicals
CAS: 1430064-74-6
Smiles: [H][C@@]12CC[C@H](C(=O)Cn3nccn3)[C@@]1(C)CC[C@@]1([H])[C@@]2([H])CC[C@]2([H])C[C@](C)(O)CC[C@]12[H]
Formula: C23H35N3O2
Pathway: N/A
Target: N/A
Receptor: N/A
Bioactivity: SGE516 is a neuroactive steroid and a positive allosteric modulator of both gamma- and delta-containing GABAA receptors. SGE516 reduces neuronal firing rates and epileptiform activity in vitro. SGE-516 protects against acute seizures and reduces neuronal cell death.
Molecular Weight: 385, 552