SGE-516 | T28766

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TMC-T28766
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Product Overview

SGE-516 | T28766 | TargetMol Chemicals

CAS: 1430064-74-6

Smiles: [H][C@@]12CC[C@H](C(=O)Cn3nccn3)[C@@]1(C)CC[C@@]1([H])[C@@]2([H])CC[C@]2([H])C[C@](C)(O)CC[C@]12[H]

Formula: C23H35N3O2

Pathway: N/A

Target: N/A

Receptor: N/A

Bioactivity: SGE516 is a neuroactive steroid and a positive allosteric modulator of both gamma- and delta-containing GABAA receptors. SGE516 reduces neuronal firing rates and epileptiform activity in vitro. SGE-516 protects against acute seizures and reduces neuronal cell death.

Molecular Weight: 385, 552

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