Product Overview
SGI-1027 | T1904 | TargetMol Chemicals
CAS: 1020149-73-8
Smiles: Cc1cc(Nc2ccc(NC(=O)c3ccc(Nc4ccnc5ccccc45)cc3)cc2)nc(N)n1
Formula: C27H23N7O
Pathway: Apoptosis|||Chromatin/Epigenetic
Target: Apoptosis|||DNA Methyltransferase
Receptor: N/A
Bioactivity: SGI-1027 is an effective and selective inhibitor of DNA methyltransferase (DNMT). The IC50 of SGI-1027 against DNMT1, DNMT3A, and DNMT3B are 6, 8, 7.5 μM, respectively.
Molecular Weight: 461, 529
