Product Overview
SI-2 | T28773 | TargetMol Chemicals
CAS: 223788-33-8
Smiles: C\C(=N/Nc1nc2ccccc2n1C)c1ccccn1
Formula: C15H15N5
Pathway: N/A
Target: N/A
Receptor: N/A
Bioactivity: SI-2 is an inhibitor (SMI) of steroid receptor coactivator-3 (SRC-3 or AIB1). SI-2 can selectively reduce the transcriptional activities and the protein concentrations of SRC-3 in cells, and selectively induce breast cancer cell death with IC50 values in the low nanomolar range (3-20 nM), but not affect normal cell viability.
Molecular Weight: 265, 32
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