Silybin B | TN2211

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TMC-TN2211
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Silybin B | TN2211 | TargetMol Chemicals

CAS: 142797-34-0

Smiles: COc1cc(ccc1O)[C@@H]1Oc2cc(ccc2O[C@H]1CO)[C@H]1Oc2cc(O)cc(O)c2C(=O)[C@@H]1O

Formula: C25H22O10

Pathway: Immunology/Inflammation|||Membrane transporter/Ion channel|||Metabolism

Target: Calcium Channel|||ROS

Receptor: N/A

Bioactivity: Silybin B and silybin A are potent inhibitors of both raloxifene 4'- and 6-glucuronidation in all enzyme systems; they show strong effects on cell growth inhibition and apoptosis induction in human chronic myeloid leukemia K562 cells. Silybin B exhibits 1, 1-diphenyl-2-picrylhydrazyl (DPPH) radical scavenging activity.

Molecular Weight: 482, 441

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