Product Overview
Simufilam dihydrochloride | T9172 | TargetMol Chemicals
CAS: 2480226-06-8
Smiles: [H]Cl.O=C1N(CC2=CC=CC=C2)C3(CCN(C)CC3)NC1.[H]Cl
Formula: C15H23Cl2N3O
Pathway: Others
Target: Others
Receptor: N/A
Bioactivity: Simufilam dihydrochloride is a low toxicity, orally active filamin A (FLNA) activator, which can be used for the research of Alzheimer's disease. Simufilam dihydrochloride preferentially binds altered FLNA and restores its native conformation, restoring receptor and synaptic activities and reducing its α7nAChR/TLR4 associations and downstream pathologies.
Molecular Weight: 332, 3
