Product Overview
Sinapinic Acid | T3753 | TargetMol Chemicals
CAS: 530-59-6
Smiles: COc1cc(\C=C\C(O)=O)cc(OC)c1O
Formula: C11H12O5
Pathway: Apoptosis|||Chromatin/Epigenetic|||DNA Damage/DNA Repair|||Endocrinology/Hormones|||Immunology/Inflammation|||Metabolism|||NF-Κb
Target: Apoptosis|||RAAS|||Reactive Oxygen Species|||HDAC
Receptor: N/A
Bioactivity: Sinapic acid protects the rat liver from CCl4-induced inflammation, most likely by acting as a free radical scavenger and modulator of NF-κB p65 activation and proinflammatory cytokine expression. Sinapic acid with antioxidant role protects cardiac cells and its functions from I/R induced oxidative stress. Sinapic acid is a potentially useful agent for the protection against liver fibrosis and cirrhosis. Sinapic acid prevents the alterations in the levels of lipids and lipoproteins by virtue of its anti-lipidaemic effect in isoproterenol induced myocardial infarcted rats. Sinapic acid ameliorates hyperglycemia through PLC-PKC signals to enhance the glucose utilization in diabetic rats.
Molecular Weight: 224, 212
