Product Overview
Sitravatinib | T4349 | TargetMol Chemicals
CAS: 1123837-84-2
Smiles: COCCNCc1ccc(nc1)-c1cc2nccc(Oc3ccc(NC(=O)C4(CC4)C(=O)Nc4ccc(F)cc4)cc3F)c2s1
Formula: C33H29F2N5O4S
Pathway: Angiogenesis|||Tyrosine Kinase/Adaptors
Target: Discoidin Domain Receptor (DDR)|||VEGFR|||FLT|||Trk receptor|||TAM Receptor|||c-Kit|||Ephrin Receptor
Receptor: N/A
Bioactivity: Sitravatinib (MGCD516) is an inhibitor targeting multiple RTKs involved in driving sarcoma cell growth, including c-Met, c-Kit, PDGFRα/β, PDGFR, and Axl.
Molecular Weight: 629, 68