Product Overview
SKF-86002 | T2367 | TargetMol Chemicals
CAS: 72873-74-6
Smiles: Fc1ccc(cc1)-c1nc2SCCn2c1-c1ccncc1
Formula: C16H12FN3S
Pathway: Apoptosis|||MAPK
Target: p38 MAPK|||TNF
Receptor: N/A
Bioactivity: SKF-86002 is an effective inhibitor of p38 MAP kinase (IC50: 0.5-1 uM); inhibits LPS-induced IL-1 and TNF-α production in human monocytes (IC50: 1 μM).
Molecular Weight: 297, 35
