Product Overview
SKLB-163 | T26193 | TargetMol Chemicals
CAS: 1255099-06-9
Smiles: ClCC(=O)Nc1ccc2nc(SCC(=O)NCc3ccccc3)sc2c1
Formula: C18H16ClN3O2S2
Pathway: Apoptosis|||Cell Cycle/Checkpoint|||Cytoskeletal Signaling|||MAPK|||PI3K/Akt/mTOR signaling|||Proteases/Proteasome
Target: MAPK|||Akt|||Caspase|||Rho|||JNK
Receptor: N/A
Bioactivity: SKLB-163 acts by downregulating RhoGDI, activating JNK-1 signaling pathway and caspase-3, and reducing phosphorylated Akt and p44/42 MAPK.
Molecular Weight: 405, 92
