Product Overview
Skullcapflavone I | TN5033 | TargetMol Chemicals
CAS: 41060-16-6
Smiles: COc1cc(O)c2c(oc(cc2=O)-c2ccccc2O)c1OC
Formula: C17H14O6
Pathway: Apoptosis|||GPCR/G Protein|||Immunology/Inflammation|||Proteases/Proteasome
Target: IL Receptor|||Caspase|||Prostaglandin Receptor
Receptor: N/A
Bioactivity: Skullcapflavone I has anti-inflammatory and anti-allergic potential, it can significantly inhibit LPS stimulated NO and PGE(2) release in J774A.1 macrophages and inhibit LPS induced IL-6 production in a concentration dependent manner. Skullcapflavone I selectively induces apoptosis in T-HSC/Cl-6 cells via caspase-3 and caspase-9 activation.
Molecular Weight: 314, 3
