Product Overview
SMI-16a | T3989 | TargetMol Chemicals
CAS: 587852-28-6
Smiles: CCCOc1ccc(\C=C2/SC(=O)NC2=O)cc1
Formula: C13H13NO3S
Pathway: Chromatin/Epigenetic|||JAK/STAT signaling
Target: Pim
Receptor: N/A
Bioactivity: PIM1/2 Kinase Inhibitor VI, a cell-permeable thiazolidinedione compound, acts as an effective, ATP-competitive inhibitor against Pim-1/2 kinases (IC50: 150/20 nM) while exhibiting little or no activity against a panel of 57 other kinases (≤18% inhibition at 5 μM).
Molecular Weight: 263, 31