Product Overview
SNIPER(ABL)-058 | T18695 | TargetMol Chemicals
CAS: 2222354-61-0
Smiles: CC1=CC=C(NC(C2=CC=C(CN3CCN(C(COCCOCCOCCOC4=CC(C(C5=CSC([C@H]6N(C([C@H](C7CCCCC7)NC([C@H](C)NC)=O)=O)CCC6)=N5)=O)=CC=C4)=O)CC3)C=C2)=O)C=C1NC8=NC=CC(C9=CC=CN=C9)=N8
Formula: C62H75N11O9S
Pathway: Others
Target: Others
Receptor: N/A
Bioactivity: SNIPER(ABL)-058, conjugating Imatinib (ABL inhibitor) to LCL161 derivative (IAP ligand) with a linker, induces the reduction of BCR-ABL protein with a DC50 of 10 μM[1].
Molecular Weight: 1150, 39