Product Overview
Sodium dichloroacetate | T3604 | TargetMol Chemicals
CAS: 2156-56-1
Smiles: [Na+].[O-]C(=O)C(Cl)Cl
Formula: C2HCl2NaO2
Pathway: Apoptosis|||Immunology/Inflammation|||Metabolism|||NF-Κb|||PI3K/Akt/mTOR signaling
Target: Apoptosis|||Dehydrogenase|||Reactive Oxygen Species|||PDK
Receptor: N/A
Bioactivity: Dichloroacetate, a specific inhibitor of pyruvate dehydrogenase kinase (PDK) with IC50 values of 183 and 80 μM for PDK2 and PDK4 respectively, has been shown to derepress a mitochondrial potassium-ion channel axis, trigger apoptosis in cancer cells, and inhibit tumor growth.
Molecular Weight: 150, 92
