Product Overview
Sonidegib | T1926 | TargetMol Chemicals
CAS: 956697-53-3
Smiles: C[C@H]1CN(C[C@@H](C)O1)c1ccc(NC(=O)c2cccc(-c3ccc(OC(F)(F)F)cc3)c2C)cn1
Formula: C26H26F3N3O3
Pathway: GPCR/G Protein|||Stem Cells
Target: Hedgehog/Smoothened|||Smo
Receptor: N/A
Bioactivity: LDE225 (NVP-LDE225; Erismodegib), a Smoothened (Smo) antagonist, inhibits Hedgehog (Hh) signaling with IC50 of 1.3 nM (mouse) and 2.5 nM (human), respectively.
Molecular Weight: 485, 5
