Product Overview
Spautin-1 | T1937 | TargetMol Chemicals
CAS: 1262888-28-7
Smiles: Fc1ccc(CNc2ncnc3ccc(F)cc23)cc1
Formula: C15H11F2N3
Pathway: Apoptosis|||Autophagy|||Cell Cycle/Checkpoint|||DNA Damage/DNA Repair|||Ubiquitination
Target: Apoptosis|||DUB|||Autophagy
Receptor: N/A
Bioactivity: Spautin-1 is a novel autophagy inhibitor, IM inhibited the growth of K562 cells with IC50 of 1.03 μM. In contrast, co-treatment with Spautin-1 increased IM-induced inhibition of cell viability with IC50 of 0.45 μM.
Molecular Weight: 271, 271
