Product Overview
SPDP | T6741 | TargetMol Chemicals
CAS: 68181-17-9
Smiles: O=C(CCSSc1ccccn1)ON1C(=O)CCC1=O
Formula: C12H12N2O4S2
Pathway: Others
Target: Others
Receptor: N/A
Bioactivity: SPDP is a short-chain crosslinker, which is used for amine-to-sulfhydryl conjugation via NHS-ester and pyridyldithiol reactive groups that form cleavable (reducible) disulfide bonds with cysteine sulfhydryls. SPDP could activate equal amounts of anti-CD11c and anti-CTLA-4 Abs (in borate buffered saline; pH 8.5).
Molecular Weight: 312, 36