Spebrutinib besylate | T14357

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TMC-T14357
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Product Overview

Spebrutinib besylate | T14357 | TargetMol Chemicals

CAS: 1360053-81-1

Smiles: OS(=O)(=O)c1ccccc1.COCCOc1ccc(Nc2ncc(F)c(Nc3cccc(NC(=O)C=C)c3)n2)cc1

Formula: C28H28FN5O6S

Pathway: Angiogenesis|||Tyrosine Kinase/Adaptors

Target: BTK

Receptor: N/A

Bioactivity: Spebrutinib besylate (AVL-292 benzenesulfonate; CC-292 besylate) is a Btk kinase activity inhibitor (IC50<0.5 nM, Kinact/Ki=7.69×104 M-1s-1s).

Molecular Weight: 581, 62

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