Product Overview
SPR inhibitor 3 | T16924 | TargetMol Chemicals
CAS: 1292285-54-1
Smiles: COCC(=O)NCCc1c(C)[nH]c2ccc(O)cc12
Formula: C14H18N2O3
Pathway: Others
Target: Others
Receptor: N/A
Bioactivity: SPR inhibitor 3 is an effective sepiapterin reductase inhibitor. SPR inhibitor 3 decreases neuropathic and inflammatory pain through a reduction of BH4 levels. SPR inhibitor 3 shows a high binding affinity to human SPR in a cell-free assay (IC50=74 nM) and efficiently reduces biopterin levels in a cell-based assay (IC50=5.2 μM).
Molecular Weight: 262, 309
