Product Overview
SR-4835 | T8325 | TargetMol Chemicals
CAS: 2387704-62-1
Smiles: Cn1cc(cn1)-n1cnc2c(NCc3nc4cc(Cl)c(Cl)cc4[nH]3)nc(nc12)N1CCOCC1
Formula: C21H20Cl2N10O
Pathway: Apoptosis|||Cell Cycle/Checkpoint
Target: Apoptosis|||CDK
Receptor: N/A
Bioactivity: SR-4835 is a highly selective dual inhibitor of CDK12 and CDK13(CDK12: IC50=99 nM, Kd=98 nM; CDK13: Kd=4.9 nM), which disables triple-negative breast cancer (TNBC) cells
Molecular Weight: 499, 36
