SR142948A HCl | T28845

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SR142948A HCl | T28845 | TargetMol Chemicals

CAS: 184162-21-8

Smiles: Cl.COc1cccc(OC)c1-c1cc(nn1-c1ccc(cc1C(C)C)C(=O)N(C)CCCN(C)C)C(=O)NC1(C2CC3CC(C2)CC1C3)C(O)=O

Formula: C39H52ClN5O6

Pathway: N/A

Target: N/A

Receptor: N/A

Bioactivity: SR 142948A is a non-peptide antagonist of neurotensin receptor. SR 142948A affects the expression of c-Fos and has properties of antipsychotic agent. SR 142948A blocks hypothermia and analgesia induced by neurotensin. It blocks the increase in the concentration of Ca+2 induced by the activation of phospholipase C in CHO cell model.

Molecular Weight: 722, 32

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