Product Overview
SR1664 | T23389 | TargetMol Chemicals
CAS: 1338259-05-4
Smiles: [H][C@@](C)(\N=C(/O)c1ccc2n(Cc3ccc(cc3)-c3ccccc3C(O)=O)c(C)c(C)c2c1)c1ccc(cc1)N(=O)=O
Formula: C33H29N3O5
Pathway: DNA Damage/DNA Repair|||Metabolism
Target: PPAR
Receptor: N/A
Bioactivity: SR1664 is a potent and selective PPARγ inhibitor with potential antidiabetic activity. SR1664 binds to PPARγ and potently inhibits Cdk5-mediated PPARγ phosphorylation (IC50 = 80 nM; Ki = 28.67 nM) without exhibiting PPARγ agonist activity.
Molecular Weight: 547, 611