Product Overview
SRA880 free base | T28851 | TargetMol Chemicals
CAS: 187218-90-2
Smiles: [H][C@]12C[C@H](CN(C)[C@]1([H])Cc1cccc(OC)c1C2)C(=O)N1CCN(CC1)c1ccc(cc1)[N+]([O-])=O
Formula: C26H32N4O4
Pathway: N/A
Target: N/A
Receptor: N/A
Bioactivity: SRA880 is a non-peptide antagonist of somatostatin sst1-receptor. SRA880 displayed significantly lower affinity for the other human recombinant somatostatin receptors ( pK(d) < or = 6.0). SRA880 shows a certain binding affinity to the human dopamine D4 receptors. SRA880 positively modulates release of endogenous SRIF, was found to synergize with imipramine in causing antidepressant-like effects in the tail suspension test.
Molecular Weight: 464, 566
