Product Overview
STING activator Compound 53 | T9853 | TargetMol Chemicals
CAS: 2259624-71-8
Smiles: CC(C)(c(ccc(C(NCc(c(F)cc(F)c1)c1F)=O)c1)c1N1Cc(c(F)ccc2)c2Cl)C1=O
Formula: C25H19ClF4N2O2
Pathway: Immunology/Inflammation
Target: STING
Receptor: N/A
Bioactivity: STING activator Compound 53 based on an oxindole core structure demonstrated robust on-target functional activation of STING (human EC50 185 nM) in immortalised and primary cells and a cytokine induction fingerprint consistent with STING activation.
Molecular Weight: 490, 88
