Product Overview
STOCK2S-26016 | T29161 | TargetMol Chemicals
CAS: 332922-63-1
Smiles: CCOc1ccc2nc3cc(NCc4ccco4)ccc3c(N)c2c1
Formula: C20H19N3O2
Pathway: N/A
Target: N/A
Receptor: N/A
Bioactivity: WNK-IN-B is an inhibitor of Wnk signalling. WNK-IN-B is a cell-permeable diaminoacridine derivative that targets the CCT domain of SPAK and OSR1 via reversible binding. WNK-IN-B selectively suppress hypotonic shock-induced WNK signaling pathway activation in mpkDCT and MOVAS (100 µM) cultures without affecting p38 MAPK phosphorylation.
Molecular Weight: 333, 391
