Product Overview
Sulconazole mononitrate | T6686 | TargetMol Chemicals
CAS: 61318-91-0
Smiles: O[N+]([O-])=O.Clc1ccc(CSC(Cn2ccnc2)c2ccc(Cl)cc2Cl)cc1
Formula: C18H16Cl3N3O3S
Pathway: Microbiology/Virology
Target: Antibacterial|||Antibiotic|||Antifungal
Receptor: N/A
Bioactivity: Sulconazole Nitrate is the nitrate salt form of sulconazole, a synthetic imidazole derivative with the antifungal property. Sulconazole nitrate inhibits fungal cytochrome P-450 sterol C-14 alpha-demethylation, resulting in the accumulation of fungal 14 alpha-methyl sterols and inhibition of the synthesis of ergosterol, an important component of the fungal cell membrane. Inhibition of ergosterol synthesis leads to a disruption of cell membrane permeability, and ultimately inhibition of cell wall synthesis. In addition, sulconazole nitrate seems to interfere with the autolytic degradation of fungal DNA and RNA.
Molecular Weight: 460, 75
