Product Overview
Supinoxin | T16961 | TargetMol Chemicals
CAS: 888478-45-3
Smiles: COc1cc(OC)cc(c1)N1CCN(CC1)C(=O)Nc1nc2cc(F)ccc2nc1OC
Formula: C22H24FN5O4
Pathway: Apoptosis|||Cell Cycle/Checkpoint|||DNA Damage/DNA Repair
Target: Apoptosis|||DNA/RNA Synthesis
Receptor: N/A
Bioactivity: Supinoxin is an orally active inhibitor of phosphorylated-p68 RNA helicase and a potent first-in-class anti-cancer agent. Supinoxin induces cell apoptosis and inhibits the growth of TNBC cancer cell lines (IC50s:10 nM - 20 nM).
Molecular Weight: 441, 463