Product Overview
SYN1143 | T8409 | TargetMol Chemicals
CAS: 913376-84-8
Smiles: CC(C)(CN(C(C)=C(C(Nc(cc1)cc(F)c1Oc1ccnc2cc(OC)ccc12)=O)C1=O)N1c1ccccc1)O
Formula: C31H29FN4O5
Pathway: Tyrosine Kinase/Adaptors
Target: c-Met/HGFR
Receptor: N/A
Bioactivity: AMG-1 is a potent inhibitor of human RON and c-Met.In vitro kinase assays showed that compound I is a potent inhibitor of human RON and c-Met with IC50s of 9 and 4 nmol/L, respectively.
Molecular Weight: 556, 58