Product Overview
Tacrolimus | T2144 | TargetMol Chemicals
CAS: 104987-11-3
Smiles: CO[C@@H]1C[C@@H](CC[C@H]1O)\C=C(/C)[C@H]1OC(=O)[C@@H]2CCCCN2C(=O)C(=O)[C@]2(O)O[C@@H]([C@H](C[C@H]2C)OC)[C@H](C[C@@H](C)C\C(C)=C\[C@@H](CC=C)C(=O)C[C@H](O)[C@H]1C)OC
Formula: C44H69NO12
Pathway: Autophagy|||Metabolism|||Microbiology/Virology|||Others|||PI3K/Akt/mTOR signaling
Target: Phosphatase|||Others|||Antibacterial|||Antibiotic|||mTOR|||Autophagy
Receptor: N/A
Bioactivity: Tacrolimus can bind FKBP12 to form a high-affinity complex (Ki: 0.2 nM) which inhibits the activity of the calcium/calmodulin-dependent protein phosphatase.
Molecular Weight: 804, 02
