Product Overview
TAK-441 | T21325 | TargetMol Chemicals
CAS: 1186231-83-3
Smiles: CCc1cc2n(C)c(C(=O)NC3CCN(CC3)C(=O)CO)c(OCC(F)(F)F)c2c(=O)n1CC(=O)c1ccccc1
Formula: C28H31F3N4O6
Pathway: N/A
Target: N/A
Receptor: N/A
Bioactivity: TAK-441 is a potent inhibitor of the Hedgehog (Hh) signaling pathway. TAK-441 shows activity to suppress transcription factor Gli1 mRNA expression in tumor-associated stromal tissue and inhibited tumor growth (treatment/control ratio, 3%) in a mouse medulloblastoma allograft model.
Molecular Weight: 576, 573
