Product Overview
TAK-659 hydrochloride | T4209 | TargetMol Chemicals
CAS: 1952251-28-3
Smiles: Cl.Cn1cc(cn1)-c1nc(N[C@@H]2CCCC[C@@H]2N)c(F)c2CNC(=O)c12
Formula: C17H22ClFN6O
Pathway: Angiogenesis|||Chromatin/Epigenetic|||JAK/STAT signaling|||Stem Cells|||Tyrosine Kinase/Adaptors
Target: VEGFR|||FLT|||Tyrosine Kinases|||JAK|||Syk
Receptor: N/A
Bioactivity: TAK-659 is a potent and selective inhibitor of spleen tyrosine kinase (SYK) with an IC50 value of 3.2 nM. It is selective against most other kinases, but potent toward both SYK and FLT3.
Molecular Weight: 380, 85
