Product Overview
Tanshinone IIA sulfonate sodium | T2946 | TargetMol Chemicals
CAS: 69659-80-9
Smiles: [Na+].Cc1c2c(oc1S([O-])(=O)=O)-c1ccc3c(CCCC3(C)C)c1C(=O)C2=O
Formula: C19H17NaO6S
Pathway: Membrane transporter/Ion channel|||Metabolism|||Neuroscience
Target: CaMK|||P450|||Calcium Channel
Receptor: N/A
Bioactivity: Sodium tanshinone IIA sulfonate (STS) is a water-soluble derivative of tanshinone IIA extracted from Savia miltiorrhiza; a potent negative allosteric modulator of the human purinergic receptor P2X7. Sodium Tanshinone IIA sulfonate (12.5 μM) inhibits hypoxia-induced PKG and PPAR-γ downregulation in PASMCs and distal pulmonary arteries of rats.
Molecular Weight: 396, 39
