Tat-NR2B9c acetate | T13112L1

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€989.00 - €10,506.00
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TMC-T13112L1
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Product Overview

Tat-NR2B9c acetate | T13112L1 | TargetMol Chemicals

CAS: 0

Smiles:

Formula: N/A

Pathway: Others

Target: Others

Receptor: N/A

Bioactivity: Tat-NR2B9c acetate is a postsynaptic density-95 (PSD-95) inhibitor, with EC50 values of 6.7 nM and 670 nM for PSD-95d2 (PSD-95 PDZ domain 2) and PSD-95d1, respectively. Tat-NR2B9c acetate disrupts the PSD-95/NMDAR interaction, inhibiting NR2A and NR2B binding to PSD-95 with IC50 values of 0.5 μM and 8 μM, respectively. Tat-NR2B9c acetate also inhibits neuronal nitric oxide synthase (nNOS)/PSD-95 interaction, and possesses neuroprotective efficacy.

Molecular Weight: N/A

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