Product Overview
TC-G 1005 | T8818 | TargetMol Chemicals
CAS: 1415407-60-1
Smiles: Cc1ccc(C)c(Oc2ccncc2C(=O)N2CCN(C3CC3)c3ccccc23)c1
Formula: C25H25N3O2
Pathway: GPCR/G Protein
Target: GPCR19
Receptor: N/A
Bioactivity: TC-G 1005 is a potent and selective GPBA agonist (EC50 :0.72 nM; hTGR5). Selective for TGR5 over FXR (farnesoid X receptor). Increases plasma GLP-1 levels and reduces blood glucose in mice. Orally available.
Molecular Weight: 399, 494
