Product Overview
TC-I 2014 | T17006 | TargetMol Chemicals
CAS: 1221349-53-6
Smiles: FC(F)(F)c1ccccc1-c1cc(c2[nH]c(nc2c1)C1=NOC2(C1)CCCCC2)C(F)(F)F
Formula: C23H19F6N3O
Pathway: Membrane transporter/Ion channel
Target: TRP/TRPV Channel
Receptor: N/A
Bioactivity: TC-I 2014 shows antiallodynic properties in pain models. TC-I 2014 is a potent and orally active Benzimidazole-containing transient receptor potential melastatin 8 antagonist (IC50: 0.8 nM, 3.0 nM, and 4.4 nM for canine, human and rat channels respectively).
Molecular Weight: 467, 415
