Product Overview
TCS-PIM-1-4a | T4215 | TargetMol Chemicals
CAS: 327033-36-3
Smiles: FC(F)(F)c1cccc(C=C2SC(=O)NC2=O)c1
Formula: C11H6F3NO2S
Pathway: Apoptosis|||Chromatin/Epigenetic|||JAK/STAT signaling
Target: Apoptosis|||Pim
Receptor: N/A
Bioactivity: TCS-PIM-1-4a, a Pim inhibitor, blocks mTORC1 activity through activation of AMPK and kills a wide range of both myeloid and lymphoid cell lines (IC50=0.8-40 μM).
Molecular Weight: 273, 23